Solubility of L-glutamic acid in concentrated water/ethanol solutions

In this work the solubility of metastable α-form and stable β-form L-Glutamic acid in pure water different water/ethanol mixtures at high concentrations ethanol is measured by analytical gravimetric method. The experiments are carried out over a temperature ranging from 283 to 343 K. experimental results show that lower than regardless solvent studied (water or mixtures). also highlight both polymorphs decreases with increase antisolvent concentration increases rising. Based on data obtained, enthalpy entropy dissolution estimated thanks empirical Van’t Hoff correlation. then correlated Combined Nearly Ideal Binary Solution (CNIBS/Redlich-Kister) equation parameters determined for studied.